Anti-Human HTRA1/PRSS11 Reference Antibody (Galegenimab, RUO) (HV033016)

Name: Anti-Human HTRA1/PRSS11 Reference Antibody (Galegenimab, RUO)
Brand: abinScience
SKU: HV033016
Price: 176 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HV033016
Description	Galegenimab (HV033016) is a research-grade recombinant antibody targeting High-temperature requirement A serine peptidase 1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG2-kappa
Système d'expression	Mammalian cells
Nature	Recombinant
Cible	High-temperature requirement A serine peptidase 1, Serine protease 11, HTRA1, PRSS11, HTRA, Serine protease HTRA1, L56
Niveau d'endotoxines	< 10 EU/mg as determined by LAL method.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q92743
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	FHTR2163, RG-6147, RG6417, RO-7171009, RO71710092403683-24-7
Contexte	Serine protease HTRA1 (PRSS11) is a ~51 kDa protein. Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)

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Bioactivity

SEC-HPLC detection for Research Grade Galegenimab.
SDS-PAGE

SDS-PAGE for Research Grade Galegenimab

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Fiche technique

Anti-Human HTRA1/PRSS11 Reference Antibody (Galegenimab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Anti-Human HTRA1/PRSS11 Reference Antibody (Galegenimab, RUO) (HV033016)

Aperçu

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SDS