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InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191) (HV033010)

InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191)
InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191)
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  • 100ug
  • 1mg
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Overview
Catalog No.HV033010
Description
InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191) [Iv0191] (HV033010) is a human monoclonal antibody detecting High-temperature requirement A serine peptidase 1 in Blocking, ELISA. Suitable for Human.
Species reactivityHuman
ApplicationsBlocking, ELISA
Host speciesHuman
IsotypeIgG2, kappa
Clone IDIv0191
Clonality Monoclonal
Target High-temperature requirement A serine peptidase 1, Serine protease 11, HTRA1, PRSS11, HTRA, Serine protease HTRA1, L56
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Associated products pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Accession Q92743
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Serine protease HTRA1 (PRSS11) is a ~51 kDa protein. Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins.

Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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