Anti-Human HTRA1/PRSS11 Reference Antibody (Galegenimab, RUO) (HV033016)

Name: Anti-Human HTRA1/PRSS11 Reference Antibody (Galegenimab, RUO)
Brand: abinScience
SKU: HV033016
Price: 176 USD
Availability: InStock

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概要

カタログ番号	HV033016
説明	Galegenimab (HV033016) is a research-grade recombinant antibody targeting High-temperature requirement A serine peptidase 1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG2-kappa
発現システム	Mammalian cells
性質	Recombinant
ターゲット	High-temperature requirement A serine peptidase 1, Serine protease 11, HTRA1, PRSS11, HTRA, Serine protease HTRA1, L56
エンドトキシンレベル	< 10 EU/mg as determined by LAL method.
純度	>95% as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q92743
形態	Liquid
保存バッファー	0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	FHTR2163, RG-6147, RG6417, RO-7171009, RO71710092403683-24-7
背景	Serine protease HTRA1 (PRSS11) is a ~51 kDa protein. Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins.
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)

イメージ

Bioactivity

SEC-HPLC detection for Research Grade Galegenimab.
SDS-PAGE

SDS-PAGE for Research Grade Galegenimab

参考文献

データシート

Anti-Human HTRA1/PRSS11 Reference Antibody (Galegenimab, RUO).pdf

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Anti-Human HTRA1/PRSS11 Reference Antibody (Galegenimab, RUO) (HV033016)

概要

イメージ

参考文献

データシート

SDS