Anti-Human oxMIF Reference Antibody (Imalumab, RUO) (HB816016)

Name: Anti-Human oxMIF Reference Antibody (Imalumab, RUO)
Brand: abinScience
SKU: HB816016
Price: 176 USD
Availability: InStock

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Спецификация:

100ug
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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HB816016

Описание

Imalumab (HB816016) is a research-grade recombinant antibody targeting MIF. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Реактивность видов

Human

Применения

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Хозяинский вид

Human

Клоональность

Monoclonal

Изотип

IgG1-kappa

Система экспрессии

Mammalian cells

Цель

oxMIF, L-dopachrome isomerase, L-dopachrome tautomerase, GIF, Macrophage migration inhibitory factor, MMIF, Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GLIF

Уровень эндотоксинов

< 10 EU/mg

Чистота

>95% purity as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P14174

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Альтернативные названия

BAX069, BAX69, 1430205-07-4

Фон

Macrophage migration inhibitory factor (MIF/GIF) is a ~12 kDa protein. Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

1. Oddo, M. et al. (2005) Infection and immunity 73, 3783-6. PMID: 15908412

2. Emonts, M. et al. (2007) Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 44, 1321-8. PMID: 17443469

3. Fan, C. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 10994-9. PMID: 23776208

4. Tan, TH. et al. (2001) The Biochemical journal 357, 373-83. PMID: 11439086

Примечание

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Изображения

Bioactivity

Detects MIF/GIF in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Imalumab.

Ссылки

Даташит

Anti-Human oxMIF Reference Antibody (Imalumab, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа