Anti-Human MIF Recombinant Antibody (SAA0115) (HB816107)

Name: Anti-Human MIF Recombinant Antibody (SAA0115)
Brand: abinScience
SKU: HB816107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HB816107
Species reactivity	Human
Applications	FCM
Host species	Human
Isotype	IgG1, kappa
Clone ID	SAA0115
Clonality	Monoclonal
Target	MIF, L-dopachrome isomerase, L-dopachrome tautomerase, GIF, Macrophage migration inhibitory factor, MMIF, Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GLIF
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P14174
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Macrophage migration inhibitory factor (MIF/GIF) is a ~12 kDa protein. Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. 1. Oddo, M. et al. (2005) Infection and immunity 73, 3783-6. PMID: 15908412 2. Emonts, M. et al. (2007) Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 44, 1321-8. PMID: 17443469 3. Fan, C. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 10994-9. PMID: 23776208 4. Tan, TH. et al. (2001) The Biochemical journal 357, 373-83. PMID: 11439086
References	1. Stamps SL, et al. Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants. Biochemistry. 2000 Aug 15;39(32):9671-8.8 [HB816107]
Note	For research use only.

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Anti-Human MIF Recombinant Antibody (SAA0115).pdf

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Anti-Human MIF Recombinant Antibody (SAA0115) (HB816107)

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