Anti-Human PD-1 & VEGFA Bispecific Reference Antibody (Ivonescimab, RUO) (HB941056)

Name: Anti-Human PD-1 & VEGFA Bispecific Reference Antibody (Ivonescimab, RUO)
Brand: abinScience
SKU: HB941056
Price: 400 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HB941056
Descripción	Ivonescimab (HB941056) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1-kappa-[scFv]2
Aplicaciones probadas	WB, FCM
Objetivo	CD279, PD1, PDCD1, Programmed cell death protein 1, Protein PD-1, L-VEGF, N-VEGF, VEGF, VEGFA, VPF, Vascular endothelial growth factor A, long form, Vascular permeability factor
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q15116 & P15692
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	TetravalentBispecific, AK112, AK-112, AK1122428381-53-5
Fondo	Ivonescimab (AK112) is a PD-1/VEGF Bispecific Antibody. Ivonescimab can be used for cancer research.
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Imágenes

Bioactivity

Detects VEGF165 in indirect ELISA.
Bioactivity

Detects recombinant human PD1 (Cat No.: HS870021) in indirect ELISA.
Flow CytoMetry

Flow-cytometry using FITC anti-human VEGFA&PD1 antibody. U87 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human VEGFA&PD1 monoclonal antibody (Catalog: HB941056, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-VEGFA/VEGF165 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human VEGFA/VEGF165 (Catalog No: HB941011)
Lane 2: negative control
Flow cytometry

Flow-cytometry using anti-human VEGFA antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human VEGFA monoclonal antibody (Catalog HB941056, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
SDS-PAGE

SDS-PAGE for Research Grade Ivonescimab

Referencias

Datasheet

Anti-Human PD-1 & VEGFA Bispecific Reference Antibody (Ivonescimab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

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Working Solution

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