Anti-Human GDF-8/Myostatin Reference Antibody (Landogrozumab, RUO) (HT343016)

Name: Anti-Human GDF-8/Myostatin Reference Antibody (Landogrozumab, RUO)
Brand: abinScience
SKU: HT343016
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
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50mg
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SDS

Vista general

Número de catálogo	HT343016
Descripción	Landogrozumab (HT343016) is a research-grade recombinant antibody targeting GDF-8. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG4-kappa
Sistema de expresión	Mammalian cells
Objetivo	GDF-8, GDF8, MSTN, Myostatin, Growth/differentiation factor 8
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	O14793
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	LY-2495655, 1391726-30-9
Fondo	Growth/differentiation factor 8 (MSTN/GDF8) is a ~42 kDa protein. Acts specifically as a negative regulator of skeletal muscle growth.
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

Imágenes

Bioactivity

SEC-HPLC detection for Research Grade Landogrozumab.
Flow Cytometry

Flow-cytometry using anti-human MSTN antibody. LNCAP cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human MSTN monoclonal antibody (Catalog HT343016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
SDS-PAGE

SDS-PAGE for Research Grade Landogrozumab