Anti-Human IL-3R alpha Reference Antibody (Lixarkitug, RUO) (HX913036)

Name: Anti-Human IL-3R alpha Reference Antibody (Lixarkitug, RUO)
Brand: abinScience
SKU: HX913036
Price: 176 USD
Availability: InStock

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概要
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データシート
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概要

カタログ番号	HX913036
説明	lixarkitug (HX913036) is a research-grade recombinant antibody targeting CD123. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
種反応性	Human
アプリケーション	ELISA, FACS, Functional assay
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
ターゲット	CD123, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, IL3R, IL3RA, Interleukin-3 receptor subunit alpha
エンドトキシンレベル	< 10 EU/mg
純度	>95% as determined by SDS-PAGE
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P26951
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	CAS: 3035710-69-8
背景	Interleukin-3 receptor subunit alpha (IL3RA) is a ~43 kDa protein. Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program. 1. Huang, S. et al. (1999) Stem cells (Dayton, Ohio) 17, 265-72. PMID: 10527461
注意事項	For research use only.