Anti-Human TFPI Reference Antibody (Marstacimab, RUO) (HY403036)

Name: Anti-Human TFPI Reference Antibody (Marstacimab, RUO)
Brand: abinScience
SKU: HY403036
Price: 176 USD
Availability: InStock

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100ug
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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HY403036
説明	Marstacimab (HY403036) is a research-grade recombinant antibody targeting Extrinsic pathway inhibitor. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1-lambda
発現システム	Mammalian cells
ターゲット	Extrinsic pathway inhibitor, Lipoprotein-associated coagulation inhibitor, TFPI, EPI, LACI, TFPI1, Tissue factor pathway inhibitor
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P10646
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	PF-06741086, 1985638-39-8
背景	Tissue factor pathway inhibitor (TFPI) is a ~35 kDa protein. Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

イメージ

SEC-HPLC

SEC-HPLC detection for Research Grade Marstacimab.
Bioactivity

Detects TFPI in indirect ELISAs.
Flow Cytometry

Flow-cytometry using anti-human TFPI antibody. HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human TFPI monoclonal antibody (Catalog HY403036, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
SDS-PAGE

SDS-PAGE for Research Grade Marstacimab