Anti-Human TFPI Reference Antibody (Befovacimab, RUO) (HY403016)

Name: Anti-Human TFPI Reference Antibody (Befovacimab, RUO)
Brand: abinScience
SKU: HY403016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	HY403016
Description	Befovacimab (HY403016) is a research-grade recombinant antibody targeting Extrinsic pathway inhibitor. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG2-lambda
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Extrinsic pathway inhibitor, Lipoprotein-associated coagulation inhibitor, TFPI, EPI, LACI, TFPI1, Tissue factor pathway inhibitor
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P10646
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Tissue factor pathway inhibitor (TFPI) is a ~35 kDa protein. Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SEC-HPLC

SEC-HPLC detection for Research Grade Befovacimab.
Bioactivity

Detects TFPI in indirect ELISAs.
Flow Cytometry

Flow-cytometry using anti-human TFPI antibody. HepG-2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human TFPI monoclonal antibody (Catalog HY403016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
SDS-PAGE

SDS-PAGE for Research Grade Befovacimab

References

Datasheet

Anti-Human TFPI Reference Antibody (Befovacimab, RUO).pdf

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Formula

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Recombinant Proteins

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Anti-Human TFPI Reference Antibody (Befovacimab, RUO) (HY403016)

Overview

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References

Datasheet

SDS

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