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Anti-Human IL-1 RAcP/IL-1 R3 Reference Antibody (Nadunolimab, RUO) (HV556016)

Anti-Human IL-1 RAcP/IL-1 R3 Reference Antibody (Nadunolimab, RUO)
Anti-Human IL-1 RAcP/IL-1 R3 Reference Antibody (Nadunolimab, RUO)
Anti-Human IL-1 RAcP/IL-1 R3 Reference Antibody (Nadunolimab, RUO)
Anti-Human IL-1 RAcP/IL-1 R3 Reference Antibody (Nadunolimab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHV556016
Описание
Nadunolimab (HV556016) is a research-grade recombinant antibody targeting IL-1R3. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1-kappa
Система экспрессии Mammalian cells
Цель IL-1R3, C3orf13, Interleukin-1 receptor 3, Interleukin-1 receptor accessory protein, IL1RAP, IL-1R-3, IL-1 receptor accessory protein, IL1R3, IL-1RAcP
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q9NPH3
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияCAN-04, CAN04, Nidanilimab, 2171061-85-9
Фон

Interleukin-1 receptor accessory protein (IL1RAP) is a ~65 kDa protein. Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex.

Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Изображения
  • Anti-Human IL-1 RAcP/IL-1 R3 Reference Antibody (Nadunolimab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Nadunolimab.

  • Anti-Human IL-1 RAcP/IL-1 R3 Reference Antibody (Nadunolimab, RUO)

    SDS-PAGE

    SDS-PAGE for Anti-Human IL1RAP Reference Antibody (Nadunolimab, RUO)

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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