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Anti-Human Sortilin Reference Antibody (Nivisnebart, RUO) (HV066026)

Anti-Human Sortilin Reference Antibody (Nivisnebart, RUO)
Anti-Human Sortilin Reference Antibody (Nivisnebart, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHV066026
Описание
nivisnebart (HV066026) is a research-grade recombinant antibody targeting SORT1/Gp95/Sortilin.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1, Kappa
Виды Human
Цель SORT1/Gp95/Sortilin
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Номер доступа Q99523
Форма Liquid
Реконституция Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия2923556-87-8
Фон

Sortilin (SORT1/Gp95) is a ~92 kDa protein. Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Lysosomal proteins bind specifically to the receptor in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH mediates the dissociation of the complex. The receptor is then recycled back to the Golgi for another round of trafficking through its binding to the retromer. Also required for protein transport from the Golgi apparatus to the endosomes.

1. Ni, X. et al. (2006) Traffic (Copenhagen, Denmark) 7, 889-902. PMID: 16787399
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Anti-Human Sortilin Reference Antibody (Nivisnebart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade nivisnebart

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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