Anti-Human CD276/B7-H3 & CD3 epsilon Bispecific Reference Antibody (Obrindatamab, RUO) (HV612046)

Name: Anti-Human CD276/B7-H3 & CD3 epsilon Bispecific Reference Antibody (Obrindatamab, RUO)
Brand: abinScience
SKU: HV612046
Price: 220 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HV612046
Descripción	Obrindatamab (HV612046) is a research-grade recombinant antibody targeting CD276. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	scFv with Domain Crossover, Kappa;Lambda
Aplicaciones probadas	WB
Objetivo	4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q5ZPR3 & P07766
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Bispecific, MGD009, RES281M1.1, hBRCA84D-hXR32-MP3M1.1, 2069959-72-2
Fondo	Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer.
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Imágenes

SDS-PAGE

SDS-PAGE for Research Grade Obrindatamab
Bioactivity

Detects CD276 in indirect ELISAs.
Bioactivity

Detects CD3E in indirect ELISAs.
Bioactivity

Detects CD276 in indirect ELISA.
Bioactivity

Detects Recombinant Human CD276 Protein, C-His (Cat No.: HV612011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD276 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD276 (Catalog No: HV612011)
Lane 2: negative control

Referencias

Datasheet

Anti-Human CD276/B7-H3 & CD3 epsilon Bispecific Reference Antibody (Obrindatamab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Working Solution

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Proteínas Recombinantes

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