Anti-Human CD276/B7-H3 & CD3 epsilon Bispecific Reference Antibody (Obrindatamab, RUO) (HV612046)

Name: Anti-Human CD276/B7-H3 & CD3 epsilon Bispecific Reference Antibody (Obrindatamab, RUO)
Brand: abinScience
SKU: HV612046
Price: 220 USD
Availability: InStock

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100ug
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SDS

Обзор

Каталожный номер	HV612046
Описание	Obrindatamab (HV612046) is a research-grade recombinant antibody targeting CD276. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	scFv with Domain Crossover, Kappa;Lambda
Проверенные приложения	WB
Цель	4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q5ZPR3 & P07766
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Bispecific, MGD009, RES281M1.1, hBRCA84D-hXR32-MP3M1.1, 2069959-72-2
Фон	Obrindatamab is a humanized anti-B7-H3/CD3 bispecific antibody. Obrindatamab binds to B7-H3 and CD3, thereby mediating redirected cytotoxic T-lymphocyte (CTL) activity against B7-H3-expressing cancer cells. Obrindatamab can be used in research of cancer.
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Изображения

SDS-PAGE

SDS-PAGE for Research Grade Obrindatamab
Bioactivity

Detects CD276 in indirect ELISAs.
Bioactivity

Detects CD3E in indirect ELISAs.
Bioactivity

Detects CD276 in indirect ELISA.
Bioactivity

Detects Recombinant Human CD276 Protein, C-His (Cat No.: HV612011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD276 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD276 (Catalog No: HV612011)
Lane 2: negative control

Ссылки

Даташит

Anti-Human CD276/B7-H3 & CD3 epsilon Bispecific Reference Antibody (Obrindatamab, RUO).pdf

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Formula

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