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Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO) (HY328186)

Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO)
Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO)
Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO)
Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO)
Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO)
Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

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  • Даташит

  • SDS

Обзор
Каталожный номерHY328186
Описание
Pacibekitug (HY328186) is a research-grade recombinant antibody targeting Hybridoma growth factor. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG2-kappa
Проверенные приложения WB
Цель B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, Interleukin-6
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P05231
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия2948444-06-0
Фон

Interleukin-6 (IL6) is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). IL6 is the therapeutic target of tocilizumab (Actemra).

Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)
Изображения
  • Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Pacibekitug.

  • Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO)

    Bioactivity

    Detects recombinant IL6 (Catalog No: HY328021) in indirect ELISA.

  • Anti-Human IL-6 Reference Antibody (Pacibekitug, RUO)

    Western blot

    Western blot analysis was performed using anti-IL6 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human IL6 (Catalog No: HY328021)
    Lane 2: Negative control

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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