





| Каталожный номер | HY328186 | ||||
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| Описание |
Pacibekitug (HY328186) is a research-grade recombinant antibody targeting Hybridoma growth factor. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Реактивность видов | Human | ||||
| Применения | ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB | ||||
| Хозяинский вид | Human | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG2-kappa | ||||
| Проверенные приложения | WB | ||||
| Цель | B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IFNB2, IL-6, IL6, Interferon beta-2, Interleukin-6 | ||||
| Уровень эндотоксинов | < 10 EU/mg | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | P05231 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Альтернативные названия | 2948444-06-0 | ||||
| Фон | Interleukin-6 (IL6) is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). IL6 is the therapeutic target of tocilizumab (Actemra). | ||||
| Примечание | For research use only. Not suitable for clinical or therapeutic use. | ||||
| Isotype Control | Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107) |

SDS-PAGE for Research Grade Pacibekitug.

Detects recombinant IL6 (Catalog No: HY328021) in indirect ELISA.

Western blot analysis was performed using anti-IL6 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human IL6 (Catalog No: HY328021)
Lane 2: Negative control




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