Research Grade produvofusp (HY505016)

Name: Research Grade produvofusp
Brand: abinScience
SKU: HY505016
Price: 370 USD
Availability: InStock

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100ug
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5mg
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50mg
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Número de catálogo	HY505016
Descripción	produvofusp (HY505016) is a research-grade recombinant antibody. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Aplicaciones	ELISA, Functional assay, Research in vivo
Clonalidad	Monoclonal
Sistema de expresión	Mammalian cells
Naturaleza	Recombinant
Nivel de endotoxinas	< 10 EU/mg as determined by LAL method.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CAS: 2925698-93-5
Fondo	Complement factor H (CFH) is a ~139 kDa protein. Glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. 1. Kajander, T. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 2897-902. PMID: 21285368 2. Morgan, HP. et al. (2011) Nature structural & molecular biology 18, 463-70. PMID: 21317894 3. Blaum, BS. et al. (2015) Nature chemical biology 11, 77-82. PMID: 25402769 4. Wu, J. et al. (2009) Nature immunology 10, 728-33. PMID: 19503104 5. Kennedy, AT. et al. (2016) Journal of immunology (Baltimore, Md. : 1950) 196, 1239-48. PMID: 26700768 6. Hocking, HG. et al. (2008) The Journal of biological chemistry 283, 9475-87. PMID: 18252712 7. Simon, N. et al. (2013) Cell host & microbe 13, 29-41. PMID: 23332154 8. Xue, X. et al. (2017) Nature structural & molecular biology 24, 643-651. PMID: 28671664 9. Losse, J. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 912-21. PMID: 20008295 10. DiScipio, RG. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 160, 4057-66. PMID: 9558116
Nota	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade produvofusp

Referencias

Datasheet

Research Grade produvofusp.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

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Kits de Ensayo

Research Grade produvofusp (HY505016)

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Referencias

Datasheet

SDS