Anti-Human PD-1 & PD-L1 Bispecific Reference Antibody (Reozalimab, RUO) (HV974216)

Name: Anti-Human PD-1 & PD-L1 Bispecific Reference Antibody (Reozalimab, RUO)
Brand: abinScience
SKU: HV974216
Price: 400 USD
Availability: InStock

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100ug
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Даташит
SDS

Обзор

Каталожный номер	HV974216
Описание	Reozalimab (HV974216) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Human
Применения	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	Ig(G1-kappa_G1-lambda2)
Проверенные приложения	WB, FCM
Цель	B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, CD279, PD1, PDCD1, Programmed cell death protein 1, Protein PD-1
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q9NZQ7 & Q15116
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Bispecific, IBI318, IBI-318, IBI318, 2445259-99-2
Фон	Reozalimab is a bispecific antibody targeting to PD-1/PD-L1. Reozalimab mediates antibody-dependent cell cytotoxicity in cancer research.
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

Bioactivity

Detects PDL1 in indirect ELISA.
Bioactivity

Detects recombinant human PD1 (Cat No.: HS870021) in indirect ELISA.
Flow CytoMetry

Flow-cytometry using anti-human CD274 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD274 monoclonal antibody (Catalog: HV974216) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-CD274/PD-L1/B7-H1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD274/PD-L1/B7-H1 (Catalog No: HV974011)
Lane 2: negative control

Ссылки

Даташит

Anti-Human PD-1 & PD-L1 Bispecific Reference Antibody (Reozalimab, RUO).pdf

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Formula

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