





| カタログ番号 | HB191026 |
|---|---|
| 説明 |
Research Grade Rilotumumab (HB191026) is a human monoclonal antibody detecting SF in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2-kappa |
| 発現システム | Mammalian cells |
| 種 | Human |
| ターゲット | SF, HPTA, Hepatopoietin-A, Hepatocyte growth factor, Scatter factor, HGF |
| エンドトキシンレベル | < 10 EU/mg |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P14210 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | 872514-65-3 |
| 背景 | Hepatocyte growth factor (SF,HPTA,Hepatopoietin-A,Hepatocyte growth factor,Scatter factor,HGF) is a ~83 kDa protein. Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation. 1. Tolbert, WD. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13264-9. PMID: 20624990 2. Stamos, J. et al. (2004) The EMBO journal 23, 2325-35. PMID: 15167892 3. Hashimoto, T. et al. (2010) The FEBS journal 277, 4888-900. PMID: 20977675 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107) |

Detects HGF in indirect ELISAs.

SEC-HPLC detection for Research Grade Rilotumumab.

SDS-PAGE for Research Grade Rilotumumab.






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