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Anti-Human HGF Reference Antibody (Rilotumumab, RUO) (HB191026)

Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
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  • 100ug
  • 1mg
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  • 概要

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概要
カタログ番号HB191026
説明
Research Grade Rilotumumab (HB191026) is a human monoclonal antibody detecting SF in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
  • ●Multi-Application — Validated across multiple applications.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG2-kappa
発現システム Mammalian cells
種 Human
ターゲット SF, HPTA, Hepatopoietin-A, Hepatocyte growth factor, Scatter factor, HGF
エンドトキシンレベル < 10 EU/mg
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P14210
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名872514-65-3
背景

Hepatocyte growth factor (SF,HPTA,Hepatopoietin-A,Hepatocyte growth factor,Scatter factor,HGF) is a ~83 kDa protein. Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation.

1. Tolbert, WD. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13264-9. PMID: 20624990
2. Stamos, J. et al. (2004) The EMBO journal 23, 2325-35. PMID: 15167892
3. Hashimoto, T. et al. (2010) The FEBS journal 277, 4888-900. PMID: 20977675
注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)
イメージ
  • Anti-Human HGF Reference Antibody (Rilotumumab, RUO)

    Bioactivity

    Detects HGF in indirect ELISAs.

  • Anti-Human HGF Reference Antibody (Rilotumumab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Rilotumumab.

  • Anti-Human HGF Reference Antibody (Rilotumumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Rilotumumab.

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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