Anti-Human HGF Reference Antibody (TAK-701, RUO) (HB191046)

Name: Anti-Human HGF Reference Antibody (TAK-701, RUO)
Brand: abinScience
SKU: HB191046
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HB191046
Description	Anti-Human HGF (TAK-701) (HB191046) is a research-grade recombinant antibody targeting SF. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	TAK-701
Expression system	Mammalian cells
Clonality	Monoclonal
Target	SF, HPTA, Hepatopoietin-A, Hepatocyte growth factor, Scatter factor, HGF
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P14210
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	TAK-701, TAK701, TAK701, HuL2G7, 2G7
Background	Hepatocyte growth factor (HGF) is a ~83 kDa protein. Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation. 1. Tolbert, WD. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13264-9. PMID: 20624990 2. Stamos, J. et al. (2004) The EMBO journal 23, 2325-35. PMID: 15167892 3. Hashimoto, T. et al. (2010) The FEBS journal 277, 4888-900. PMID: 20977675
Note	For research use only. Not suitable for clinical or therapeutic use.