





| Catalog No. | HB191026 |
|---|---|
| Description |
Research Grade Rilotumumab (HB191026) is a human monoclonal antibody detecting SF in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Host species | Human |
| Isotype | IgG2-kappa |
| Expression system | Mammalian cells |
| Species | Human |
| Clonality | Monoclonal |
| Target | SF, HPTA, Hepatopoietin-A, Hepatocyte growth factor, Scatter factor, HGF |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P14210 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | 872514-65-3 |
| Background | Hepatocyte growth factor (SF,HPTA,Hepatopoietin-A,Hepatocyte growth factor,Scatter factor,HGF) is a ~83 kDa protein. Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation. 1. Tolbert, WD. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13264-9. PMID: 20624990 2. Stamos, J. et al. (2004) The EMBO journal 23, 2325-35. PMID: 15167892 3. Hashimoto, T. et al. (2010) The FEBS journal 277, 4888-900. PMID: 20977675 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

Detects HGF in indirect ELISAs.

SEC-HPLC detection for Research Grade Rilotumumab.

SDS-PAGE for Research Grade Rilotumumab.




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