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Anti-Human HGF Reference Antibody (Rilotumumab, RUO) (HB191026)

Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
Anti-Human HGF Reference Antibody (Rilotumumab, RUO)
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Overview
Catalog No.HB191026
Description
Research Grade Rilotumumab (HB191026) is a human monoclonal antibody detecting SF in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.
Highlights
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG2-kappa
Expression system Mammalian cells
Species Human
Clonality Monoclonal
Target SF, HPTA, Hepatopoietin-A, Hepatocyte growth factor, Scatter factor, HGF
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P14210
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names872514-65-3
Background

Hepatocyte growth factor (SF,HPTA,Hepatopoietin-A,Hepatocyte growth factor,Scatter factor,HGF) is a ~83 kDa protein. Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation.

1. Tolbert, WD. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13264-9. PMID: 20624990
2. Stamos, J. et al. (2004) The EMBO journal 23, 2325-35. PMID: 15167892
3. Hashimoto, T. et al. (2010) The FEBS journal 277, 4888-900. PMID: 20977675
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • Anti-Human HGF Reference Antibody (Rilotumumab, RUO)

    Bioactivity

    Detects HGF in indirect ELISAs.

  • Anti-Human HGF Reference Antibody (Rilotumumab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Rilotumumab.

  • Anti-Human HGF Reference Antibody (Rilotumumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Rilotumumab.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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