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Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO) (HV185016)

Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
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Aperçu
Numéro de catalogueHV185016
Description
Romosozumab (HV185016) is a research-grade recombinant antibody targeting SOST. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espècesHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG2-kappa
Système d'expression Mammalian cells
Cible SOST, Sclerostin
Niveau d'endotoxines < 10 EU/mg
Pureté >95% purity as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q9BQB4
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs785A070802, AMG785, CDP-7851, romosozumab-aqqg, sclerostinAb, CAS: 909395-70-6
Contexte

Sclerostin (SOST) is a ~24 kDa protein. Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Note For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)
Images
  • Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Romosozumab.

  • Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)

    Bioactivity

    Detects Human SOST in indirect ELISAs.

  • Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Romosozumab.

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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