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Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO) (HV185016)

Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)
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  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
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概要
カタログ番号HV185016
説明
Romosozumab (HV185016) is a research-grade recombinant antibody targeting SOST. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性Human
アプリケーションELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種Human
クローン性Monoclonal
アイソタイプIgG2-kappa
発現システム Mammalian cells
ターゲット SOST, Sclerostin
エンドトキシンレベル < 10 EU/mg
純度 >95% purity as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 Q9BQB4
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名785A070802, AMG785, CDP-7851, romosozumab-aqqg, sclerostinAb, CAS: 909395-70-6
背景

Sclerostin (SOST) is a ~24 kDa protein. Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

注意事項 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107)
イメージ
  • Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Romosozumab.

  • Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)

    Bioactivity

    Detects Human SOST in indirect ELISAs.

  • Anti-Human SOST/Sclerostin Reference Antibody (Romosozumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Romosozumab.

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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