Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO) (HV777016)

Name: Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO)
Brand: abinScience
SKU: HV777016
Price: 176 USD
Availability: InStock

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概要
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概要

カタログ番号	HV777016
説明	Samrotamab (HV777016) is a research-grade recombinant antibody targeting Leucine-rich repeat protein induced by beta-amyloid homolog. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1-kappa
発現システム	Mammalian cells
ターゲット	Leucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q8TF66
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	ABBV-085, PR-1498487-MMAE, PR-1498487, Samrotamabvedotin, 2052591-32-7
背景	Leucine-rich repeat-containing protein 15 (LRRC15/LIB) is a ~64 kDa protein. (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein. Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells. 1. Song, J. et al. (2022) PLoS biology 20, e3001805. PMID: 36228039 2. Shilts, J. et al. (2023) PLoS biology 21, e3001959. PMID: 36735681 3. Loo, L. et al. (2023) PLoS biology 21, e3001967. PMID: 36757924
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

イメージ

Bioactivity

SEC-HPLC detection for Research Grade Samrotamab.
SDS-PAGE

SDS-PAGE for Research Grade Samrotamab

参考文献

データシート

Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO).pdf

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Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO) (HV777016)

概要

イメージ

参考文献

データシート

SDS

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