Anti-Human LRRC15/LIB Recombinant Antibody (SAA0773) (HV777107)

Name: Anti-Human LRRC15/LIB Recombinant Antibody (SAA0773)
Brand: abinScience
SKU: HV777107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HV777107
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0773
Clonality	Monoclonal
Target	Leucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q8TF66
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Leucine-rich repeat-containing protein 15 (LRRC15/LIB) is a ~64 kDa protein. (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein. Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells. 1. Song, J. et al. (2022) PLoS biology 20, e3001805. PMID: 36228039 2. Shilts, J. et al. (2023) PLoS biology 21, e3001959. PMID: 36735681 3. Loo, L. et al. (2023) PLoS biology 21, e3001967. PMID: 36757924
Note	For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human LRRC15/LIB Antibody (SAA0773)
Flow Cytometry

Flow-cytometry using anti-human LRRC15 antibody.LRRC15 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human LRRC15 antibody monoclonal antibody (Catalog # HV777107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet

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Formula

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Working Solution

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Overview