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Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO) (HV777016)

Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO)
Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO)
Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO)
Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерHV777016
Описание
Samrotamab (HV777016) is a research-grade recombinant antibody targeting Leucine-rich repeat protein induced by beta-amyloid homolog. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1-kappa
Система экспрессии Mammalian cells
Цель Leucine-rich repeat protein induced by beta-amyloid homolog, LRRC15, Leucine-rich repeat-containing protein 15, LIB, hLib
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q8TF66
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияABBV-085, PR-1498487-MMAE, PR-1498487, Samrotamabvedotin, 2052591-32-7
Фон

Leucine-rich repeat-containing protein 15 (LRRC15/LIB) is a ~64 kDa protein. (Microbial infection) Modulates the ability of SARS-CoV-2 to infect host cells through interaction with the spike protein. Does not act as a SARS-CoV-2 entry receptor but sequesters virions and antagonizes in trans SARS-CoV-2 infection of ACE2(+) cells when expressed on nearby cells.

1. Song, J. et al. (2022) PLoS biology 20, e3001805. PMID: 36228039
2. Shilts, J. et al. (2023) PLoS biology 21, e3001959. PMID: 36735681
3. Loo, L. et al. (2023) PLoS biology 21, e3001967. PMID: 36757924
Примечание For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
Изображения
  • Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Samrotamab.

  • Anti-Human LRRC15/LIB Reference Antibody (Samrotamab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Samrotamab

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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