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Research Grade Sotiburafusp Alfa
Research Grade Sotiburafusp Alfa
Research Grade Sotiburafusp Alfa
Research Grade Sotiburafusp Alfa
Research Grade Sotiburafusp Alfa
Research Grade Sotiburafusp Alfa
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Даташит

  • SDS

Обзор
Каталожный номерHV974436
Описание
Sotiburafusp Alfa (HV974436) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовHuman
ПримененияELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1-kappa, fused with humanized vascular endothelial growth factor receptor 1/VEGFR-1 extracellular domain fragment
Проверенные приложения WB
Цель B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1
Уровень эндотоксинов < 10 EU/mg
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q9NZQ7
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4.

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Информация об использовании продукта
Применение Разбавление
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия2637466-37-4
ФонSotiburafusp alfa is a bispecific fusion protein, which is a humanized VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) fused via the peptide linker 101GGSGGSGGSGGSGGS115 to the N-terminus of the heavy chain (116-564) of a humanized IgG1-kappa anti-human PD-L1 heavy chain variant L352>A, L353>A. Sotiburafusp alfa is also an angiogenesis inhibitor.
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Research Grade Sotiburafusp Alfa

    SDS-PAGE

    SDS-PAGE for Research Grade Sotiburafusp Alfa.

  • Research Grade Sotiburafusp Alfa

    Bioactivity

    Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.

  • Research Grade Sotiburafusp Alfa

    Western blot

    Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human PDL1 (Catalog No: HV974011)
    Lane 2: Negative control

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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