Anti-Human clfA/Clumping factor A Reference Antibody (Tefibazumab, RUO) (JN060016)

Name: Anti-Human clfA/Clumping factor A Reference Antibody (Tefibazumab, RUO)
Brand: abinScience
SKU: JN060016
Price: 176 USD
Availability: InStock

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Изображения
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Даташит
SDS

Обзор

Каталожный номер	JN060016
Описание	Tefibazumab (JN060016) is a research-grade recombinant antibody targeting clfAClumping factor A. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видов	Staphylococcus aureus
Применения	ELISA, Functional assay, Research in vivo
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1-kappa
Система экспрессии	Mammalian cells
Цель	clfA Clumping factor A
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% purity as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q53653, Q2G015, Q5HHM8
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Aurexis, 521079-87-8
Фон	Clumping factor A (clfAClumping factor A) is a ~97 kDa protein. Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing. Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed. Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis.
Примечание	For research use only. Not suitable for clinical or therapeutic use.

Изображения

Bioactivity

SEC-HPLC detection for Research Grade Tefibazumab.
SDS-PAGE

SDS-PAGE for Research Grade Tefibazumab.

Ссылки

Даташит

Anti-Human clfA/Clumping factor A Reference Antibody (Tefibazumab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Volume

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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