Anti-ClfA Reference Antibody (AZD7745, RUO) (JN060026)

Name: Anti-ClfA Reference Antibody (AZD7745, RUO)
Brand: abinScience
SKU: JN060026
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	JN060026
Description	Research Grade Anti-ClfA Antibody (AZD7745) [AZD7745] (JN060026) is a human monoclonal antibody detecting Clumping factor A in ELISA, Functional assay, Research in vivo. Highlights ●Multi-Application — Validated across multiple applications.
Species reactivity	Staphylococcus aureus
Applications	ELISA, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	AZD7745
Clonality	Monoclonal
Target	Clumping factor A, Fibrinogen receptor A, Fibrinogen-binding protein A, clfA
Endotoxin level	< 1EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q53653, Q2G015, Q5HHM8
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	SAR114
Background	Clumping factor A (ClfA) is a ~97 kDa protein. Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing. Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed. Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis.
Note	For research use only.

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Anti-ClfA Reference Antibody (AZD7745, RUO).pdf

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Anti-ClfA Reference Antibody (AZD7745, RUO) (JN060026)

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