Anti-Human clfA/Clumping factor A Reference Antibody (Tefibazumab, RUO) (JN060016)

Name: Anti-Human clfA/Clumping factor A Reference Antibody (Tefibazumab, RUO)
Brand: abinScience
SKU: JN060016
Price: 176 USD
Availability: InStock

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Overview

Catalog No.	JN060016
Description	Tefibazumab (JN060016) is a research-grade recombinant antibody targeting clfAClumping factor A. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Staphylococcus aureus
Applications	ELISA, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-kappa
Expression system	Mammalian cells
Clonality	Monoclonal
Target	clfA Clumping factor A
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q53653, Q2G015, Q5HHM8
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Aurexis, 521079-87-8
Background	Clumping factor A (clfAClumping factor A) is a ~97 kDa protein. Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing. Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed. Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis.
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

SEC-HPLC detection for Research Grade Tefibazumab.
SDS-PAGE

SDS-PAGE for Research Grade Tefibazumab.

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Datasheet

Anti-Human clfA/Clumping factor A Reference Antibody (Tefibazumab, RUO).pdf

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Anti-Human clfA/Clumping factor A Reference Antibody (Tefibazumab, RUO) (JN060016)

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