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Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO) (CV678016)

Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO)
Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO)
Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO)
Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO)
Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO)
Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерCV678016
Описание
Tirnovetmab (CV678016) is a research-grade recombinant antibody targeting IL-31. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовCanine
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видCanine
КлоональностьMonoclonal
ИзотипIgG2-Kappa
Система экспрессии Mammalian cells
Цель IL-31, Interleukin-31, IL31
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа C7G0W1
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияKIND-016, 2364504-80-1
ФонTirnovetmab (KIND-016) is an antibody. Tirnovetmab can be used for experiment research.
• The IL-4, IL-13 and IL-31 pathways in atopic dermatitis., PMID:34106037
• IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis., PMID:37831760
• Interleukin-31: The "itchy" cytokine in inflammation and therapy., PMID:33629401
• A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1., PMID:24373353
• Seladelpar treatment reduces IL-31 and pruritus in patients with primary biliary cholangitis., PMID:38117036
• Nemolizumab: First Approval., PMID:35834124
• Nemolizumab: An Innovative Biologic Treatment to Control Interleukin 31, a Key Mediator in Atopic Dermatitis and Prurigo Nodularis., PMID:35842249
• The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching., PMID:32673566
• Pruritus as a Distinctive Feature of Type 2 Inflammation., PMID:33807098
• Targeting Interleukin-31 in Prurigo., PMID:37888922
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Tirnovetmab.

  • Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Tirnovetmab

  • Anti-Canine IL-31 Reference Antibody (Tirnovetmab, RUO)

    Bioactivity

    Detects Recombinant dog IL31 (CV678011) in indirect ELISAs.

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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