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Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO) (JN998016)

Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO)
Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO)
Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO)
Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO)
Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO)
Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO)
Цена(USD):
Спецификация:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
Количество:
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  • Обзор

  • Изображения

  • Ссылки

  • Даташит

  • SDS

Обзор
Каталожный номерJN998016
Описание
Tosatoxumab (JN998016) is a research-grade recombinant antibody targeting Alpha-hemolysin. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Реактивность видовStaphylococcus aureus
ПримененияELISA, Bioactivity: FACS, Functional assay, Research in vivo
Хозяинский видHuman
КлоональностьMonoclonal
ИзотипIgG1-lambda
Система экспрессии Mammalian cells
Цель Alpha-hemolysin, hly, Alpha-HL, Alpha-toxin, hla
Уровень эндотоксинов < 10 EU/mg
Чистота >95% purity as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа P09616
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияKBSA301, 1374419-41-6
Фон

Alpha-hemolysin (Alpha-toxin/hly) is a ~35 kDa protein. Alpha-toxin binds to the membrane of eukaryotic cells (particularly red blood cells, RBC) forming pores, resulting in hemolysis, with the release of low-molecular weight molecules leading to eventual osmotic RBC lysis. Human RBCs bind much less alpha-toxin than do rabbit RBCs. Heptamer oligomerization and pore formation is required for lytic activity.

1. Walker, B. et al. (1992) The Journal of biological chemistry 267, 10902-9. PMID: 1587866
2. Wilke, GA. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13473-8. PMID: 20624979
Примечание For research use only. Not suitable for clinical or therapeutic use.
Изображения
  • Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO)

    SEC-HPLC

    SEC-HPLC detection for Research Grade Tosatoxumab.

  • Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO)

    Bioactivity

    Detects Alpha-toxin/hly in indirect ELISAs.

  • Anti-Human Alpha‑Toxin/Hla Reference Antibody (Tosatoxumab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Tosatoxumab.

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Рекомендация

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