

| Catalog No. | DN998018 |
|---|---|
| Description |
Tosatoxumab ELISA Kit (DN998018) — Quantitative sandwich ELISA for Tosatoxumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
|
| Sample type | Plasma, Serum |
| Sensitivity | 0.156 μg/ml |
| Range | 0.31-5 μg/mL |
| Accession | P09616 |
| Applications | ELISA |
| Detection method | Colorimetric |
| Assay type | Quantitative |
| Recovery | 80-120% |
| Shipping | 2-8 ℃ |
| Stability and Storage | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| Specifications | Tosatoxumab |
| Alternate Names | KBSA301, 1374419-41-6 |
| Background | Alpha-hemolysin (Tosatoxumab) is a ~35 kDa protein. Alpha-toxin binds to the membrane of eukaryotic cells (particularly red blood cells, RBC) forming pores, resulting in hemolysis, with the release of low-molecular weight molecules leading to eventual osmotic RBC lysis. Human RBCs bind much less alpha-toxin than do rabbit RBCs. Heptamer oligomerization and pore formation is required for lytic activity. 1. Walker, B. et al. (1992) The Journal of biological chemistry 267, 10902-9. PMID: 1587866 2. Wilke, GA. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13473-8. PMID: 20624979 |
| Note | For Research Use Only. |




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