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Anti-Human CD131/CSF2RB Reference Antibody (Trabikibart, RUO) (HW498026)

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Anti-Human CD131/CSF2RB Reference Antibody (Trabikibart, RUO)
Anti-Human CD131/CSF2RB Reference Antibody (Trabikibart, RUO)
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  • 100ug
  • 1mg
  • 5mg
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Vista general
Número de catálogoHW498026
Descripción
Trabikibart (HW498026) is a research-grade recombinant antibody targeting CD131. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FCM, Functional assay, Research in vivo
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG4-kappa
Sistema de expresión Mammalian cells
Naturaleza Recombinant
Objetivo Cytokine receptor common subunit beta, IL3RB, IL5RB, CDw131, CD131, CSF2RB, GM-CSF/IL-3/IL-5 receptor common beta subunit
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P32927
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos2643974-98-3
Fondo

Cytokine receptor common subunit beta (CD131/CSF2RB) is a ~97 kDa protein. Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA. In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways. In unstimulated conditions, interacts constitutively with JAK1 and ligand binding leads to JAK1 stimulation and subsequent activation of the JAK-STAT pathway.

1. Tavernier, J. et al. (1992) Proceedings of the National Academy of Sciences of the United States of America 89, 7041-5. PMID: 1495999
2. Ogata, N. et al. (1998) Blood 91, 2264-71. PMID: 9516124
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Anti-Human CD131/CSF2RB Reference Antibody (Trabikibart, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Trabikibart

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human CD131/CSF2RB Reference Antibody (Trabikibart, RUO)

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