Anti-BKPyV VP1 Reference Antibody (Traxivitug, RUO) (VK698016)

Name: Anti-BKPyV VP1 Reference Antibody (Traxivitug, RUO)
Brand: abinScience
SKU: VK698016
Price: 370 USD
Availability: InStock

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Aperçu

Numéro de catalogue	VK698016
Description	Traxivitug (VK698016) is a research-grade recombinant antibody targeting Major capsid protein VP1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	BK polyomavirus (BKPyV)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1-lambda2
Système d'expression	Mammalian cells
Cible	Major capsid protein VP1, Major structural protein VP1
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P03088
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	2770852-89-4, MAU868
Contexte	Major capsid protein VP1 is a ~40 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with gangliosides GT1b and GD1b containing terminal alpha(2-8)-linked sialic acids on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Traxivitug.
Bioactivity

Detects recombinant BKPyV VP1 (Catalog No: VK452011) in indirect ELISA.

Reférences

Fiche technique

Anti-BKPyV VP1 Reference Antibody (Traxivitug, RUO).pdf

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Formula

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