Anti-BkPyV VP1 Reference Antibody (Potravitug, RUO) (VK452016)

Name: Anti-BkPyV VP1 Reference Antibody (Potravitug, RUO)
Brand: abinScience
SKU: VK452016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	VK452016
Description	potravitug (VK452016) is a research-grade recombinant antibody targeting Major capsid protein VP1. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
Species reactivity	BK polyomavirus (BKPyV) (Human polyomavirus 1)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1, Kappa
Species	BK polyomavirus (BKPyV) (Human polyomavirus 1)
Clonality	Monoclonal
Target	Major capsid protein VP1
Purity	>95% as determined by SDS-PAGE.
Accession	P03088
Form	Liquid
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2923558-06-7, MTX-005
Background	Major capsid protein VP1 is a ~40 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with gangliosides GT1b and GD1b containing terminal alpha(2-8)-linked sialic acids on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade potravitug

References

Datasheet

Anti-BkPyV VP1 Reference Antibody (Potravitug, RUO).pdf

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Anti-BkPyV VP1 Reference Antibody (Potravitug, RUO) (VK452016)

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References

Datasheet

SDS

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