Anti-BKPyV VP1 Reference Antibody (Traxivitug, RUO) (VK698016)

Name: Anti-BKPyV VP1 Reference Antibody (Traxivitug, RUO)
Brand: abinScience
SKU: VK698016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	VK698016
Description	Traxivitug (VK698016) is a research-grade recombinant antibody targeting Major capsid protein VP1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	BK polyomavirus (BKPyV)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1-lambda2
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Major capsid protein VP1, Major structural protein VP1
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P03088
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	2770852-89-4, MAU868
Background	Major capsid protein VP1 is a ~40 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with gangliosides GT1b and GD1b containing terminal alpha(2-8)-linked sialic acids on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Traxivitug.
Bioactivity

Detects recombinant BKPyV VP1 (Catalog No: VK452011) in indirect ELISA.

References

Datasheet

Anti-BKPyV VP1 Reference Antibody (Traxivitug, RUO).pdf

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Anti-BKPyV VP1 Reference Antibody (Traxivitug, RUO) (VK698016)

Overview

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References

Datasheet

SDS

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