Anti-Human VEGF & Angiopoietin-2 Bispecific Reference Antibody (Vanucizumab, RUO) (HT073026)

Name: Anti-Human VEGF & Angiopoietin-2 Bispecific Reference Antibody (Vanucizumab, RUO)
Brand: abinScience
SKU: HT073026
Price: 176 USD
Availability: InStock

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100ug
1mg
5mg
10mg
25mg
50mg
100mg

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SDS

Vista general

Número de catálogo	HT073026
Descripción	Vanucizumab (HT073026) is a research-grade recombinant antibody targeting Vascular endothelial growth factor A. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	human IgG1 - kappa - lambda with half-IG VL-CH1/VH-CK crossover
Sistema de expresión	Mammalian cells
Aplicaciones probadas	FCM
Objetivo	Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A, ANG-2, ANGPT2, Angiopoietin-2
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P15692 & O15123
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Bispecific, RG-7221, RG7221, RO5520985, 1448221-05-3
Fondo	Zifibancimig is an anti-VEGFA/ANGPT2 IgG1κ monoclonal antibody.
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10) (HV080407) Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

Imágenes

Bioactivity

Detects Human VEGFA in indirect ELISAs.
SEC-HPLC

SEC-HPLC detection for Research Grade Vanucizumab.
Bioactivity

Detects Human ANGPT2 in indirect ELISAs.
Flow CytoMetry

Flow-cytometry using FITC anti-human VEGFA&ANGPT2 antibody. U87 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human VEGFA&ANGPT2 monoclonal antibody (Catalog: HT073026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.