

| Catalog No. | DT073038 |
|---|---|
| Description |
Vanucizumab ELISA Kit (DT073038) — Quantitative sandwich ELISA for Vanucizumab. Sample: Plasma, Serum. Range: 0.31-5 μg/mL. Sensitivity: 0.156 μg/ml.
Highlights
|
| Sample type | Plasma, Serum |
| Sensitivity | 0.156 μg/ml |
| Range | 0.31-5 μg/mL |
| Accession | P15692 & O15123 |
| Applications | ELISA |
| Detection method | Colorimetric |
| Assay type | Quantitative |
| Recovery | 80-120% |
| Shipping | 2-8 ℃ |
| Stability and Storage | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| Specifications | Vanucizumab |
| Alternate Names | RG-7221, RG7221, RO5520985, 1448221-05-3 |
| Background | Vanucizumab (RG7221) is an experimental humanized monoclonal antibody (mAb) designed for the treatment of cancer. Vanucizumab is a bi-specific mAb composed of two different heavy chains and two different light chains. One arm of the antibody binds Angiopoietin-2 (Ang2) and the other is based on bevacizumab (Avastin), binding vascular endothelial growth factor A (VEGF-A). The antibody is designed to inhibit both VEGF-A and Ang2 simultaneously to offer superior clinical benefit compared to VEGF-A inhibition alone. This drug was developed by Genentech/Roche. On 12 Mar 2018, Roche completes a phase I trial in solid tumors (combination therapy, late-stage disease, metastatic disease, second-line therapy or greater) in Spain, France, and Belgium. |
| Note | For Research Use Only. |




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