Anti-Human OSMR beta Reference Antibody (Vixarelimab, RUO) (HV716016)

Name: Anti-Human OSMR beta Reference Antibody (Vixarelimab, RUO)
Brand: abinScience
SKU: HV716016
Price: 176 USD
Availability: InStock

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100ug
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5mg
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Vista general

Número de catálogo	HV716016
Descripción	Vixarelimab (HV716016) is a research-grade recombinant antibody targeting OSMRB. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG4-IgG1, Lambda
Sistema de expresión	Mammalian cells
Objetivo	OSMRB, IL-31R subunit beta, Oncostatin-M-specific receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31RB, IL-31R-beta, OSMR, IL-31 receptor subunit beta
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q99650
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	KPL-716, 30C6(N73D), BIIB069, BIIB-069, 2243320-83-2
Fondo	Oncostatin-M-specific receptor subunit beta (OSMR/IL-31RB) is a ~110 kDa protein. Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

Imágenes

Bioactivity

SEC-HPLC detection for Research Grade Vixarelimab.

Referencias

Datasheet

Anti-Human OSMR beta Reference Antibody (Vixarelimab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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