Anti-Human EMMPRIN/CD147 Reference Antibody (Ziralimumab, RUO) (HW664026)

Name: Anti-Human EMMPRIN/CD147 Reference Antibody (Ziralimumab, RUO)
Brand: abinScience
SKU: HW664026
Price: 176 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HW664026
説明	Ziralimumab (HW664026) is a research-grade recombinant antibody targeting CD147. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
種反応性	Human
アプリケーション	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgM-nd
発現システム	Mammalian cells
テスト済みアプリケーション	WB
ターゲット	Hepatoma-associated antigen, BSG, HAb18G, 5F7, TCSF, OK blood group antigen, Collagenase stimulatory factor, CD147, Leukocyte activation antigen M6, Basigin, Extracellular matrix metalloproteinase inducer, EMMPRIN, Tumor cell-derived collagenase stimulatory factor
エンドトキシンレベル	< 10 EU/mg
純度	>95% purity as determined by SDS-PAGE.
精製	Protein L purified from cell culture supernatant.
アクセッション番号	P35613
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	ABX-RB2, 1427008-29-4, cem2.6
背景	Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes. 1. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687 2. Redzic, JS. et al. (2011) Journal of molecular biology 411, 68-82. PMID: 21620857
注意事項	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Anti-Urushiol Reference Antibody (ALG-991, RUO) (YP340013)

イメージ

Western blot

Western blot analysis was performed using anti-CD147/BSG monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD147/BSG (Catalog No: HW664011)
Lane 2: negative control
Bioactivity

Detects recombinant CD147 (Catalog No: HW664011) in indirect ELISA.
SDS-PAGE

SDS-PAGE for Research Grade Ziralimumab