

| Каталожный номер | HB191021 |
|---|---|
| Описание |
GMP Grade Human HGF (Tag Free) (HB191021) expressed in Mammalian cells. Purity: >95% as determined by SDS-PAGE. by SDS-PAGE.
Highlights
|
| Система экспрессии | Mammalian cells |
| Номер доступа | P14210 |
| Длина белка | α chain:Gln32-Arg494 & β chain:Val495-Ser728 |
| Применения | ELISA, Functional assay |
| Виды | Homo sapiens (Human) |
| Биологическая активность | Measured by its ability to induce IL-11 secretion by Saos‑2 human osteosarcoma cells. The ED50 for this effect is ≤2.5 ng/ml.. |
| Характер | Recombinant |
| Уровень эндотоксинов | <0.01 EU/ug |
| Чистота | >95% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol, 0.01% Tween 80, pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | HGF, HPTA, Hepatocyte growth factor, Hepatocyte growth factor alpha chain, Hepatocyte growth factor beta chain, Hepatopoietin-A, SF, Scatter factor |
| Фон | Hepatocyte growth factor (SF,HPTA,Hepatopoietin-A,Hepatocyte growth factor,Scatter factor,HGF) is a ~83 kDa protein. Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation. 1. Tolbert, WD. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13264-9. PMID: 20624990 2. Stamos, J. et al. (2004) The EMBO journal 23, 2325-35. PMID: 15167892 3. Hashimoto, T. et al. (2010) The FEBS journal 277, 4888-900. PMID: 20977675 |
| Примечание | For research use only |




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