Anti-Human Coagulation Factor III/Tissue Factor Reference Antibody (Mevegtatug, RUO) (HB058086)

Name: Anti-Human Coagulation Factor III/Tissue Factor Reference Antibody (Mevegtatug, RUO)
Brand: abinScience
SKU: HB058086
Price: 370 USD
Availability: InStock

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Спецификация:

100ug
1mg

Количество:

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Каталожный номер	HB058086
Описание	Anti-Human Coagulation Factor III/Tissue Factor Reference Antibody (Mevegtatug, RUO) (HB058086) is a human monoclonal antibody detecting Coagulation Factor III/Tissue Factor.
Реактивность видов	Human
Применения	ELISA, FCM, Functional assay
Хозяинский вид	Human
Клоональность	Monoclonal
Изотип	IgG1, kappa
Цель	RecName: Full=Tissue factor; Short=TF; AltName: Full=Coagulation factor III; AltName: Full=Thromboplastin; AltName: CD_antigen=CD142; Flags: Precursor, F3, TF; Coagulation factor III; Thromboplastin, Tissue factor; pfam01108, Tissue factor. /id=PRO_0000033638., Extracellular. /evidence=ECO:0000255., T -> A (in dbSNP:rs3917604). /evidence=ECO:0000269\|Ref.9. /id=VAR_014298., /evidence=ECO:0007829\|PDB:6R2W., WKS motif., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0007829\|PDB:1UJ3., WKS motif., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0000269\|PubMed:3166978., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0007829\|PDB:2HFT., /evidence=ECO:0007829\|PDB:8CN9., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0007829\|PDB:1Z6J., /evidence=ECO:0007829\|PDB:4YLQ., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0007829\|PDB:6R2W., Interferon-alpha/beta receptor, fibronectin type III; pfam09294, /evidence=ECO:0007829\|PDB:6R2W., I -> V (in dbSNP:rs3917627). /evidence=ECO:0000269\|Ref.9. /id=VAR_014299., /evidence=ECO:0007829\|PDB:6R2W., N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255., /evidence=ECO:0007829\|PDB:6R2W., R -> W (in dbSNP:rs5901). /id=VAR_012008., N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0007829\|PDB:6R2W., WKS motif., /evidence=ECO:0007829\|PDB:3TH2., /evidence=ECO:0007829\|PDB:6R2W., TAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSP -> YSTSLELWYLWSSSLSSSWLYLYTSVERQEWGRAGRRTPH (in isoform 2). /evidence=ECO:0000303\|PubMed:12652293. /id=VSP_041896., /evidence=ECO:0007829\|PDB:1WV7., /evidence=ECO:0007829\|PDB:6R2W., /evidence=ECO:0000269\|PubMed:3166978., /evidence=ECO:0007829\|PDB:6R2W., Missing (in isoform 2). /evidence=ECO:0000303\|PubMed:12652293. /id=VSP_041897., /evidence=ECO:0007829\|PDB:1BOY., Helical. /evidence=ECO:0000255., V -> A (in Ref. 1; AAA61151). /evidence=ECO:0000305., Cytoplasmic. /evidence=ECO:0000255., S-palmitoyl cysteine. /evidence=ECO:0000269\|PubMed:3166978., /evidence=ECO:0007829\|PDB:2CEF., G -> E (in dbSNP:rs3789683). /id=VAR_052280., /evidence=ECO:0007829\|PDB:2CEF.
Уровень эндотоксинов	< 10 EU/mg as determined by LAL method.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P13726
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..
Альтернативные названия	CAS: 3074785-85-3
Фон	Tissue factor (CD142/F3) is a ~33 kDa protein. Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. CD142 is the therapeutic target of tisotumab vedotin (Tivdak).
Примечание	For research use only. Not suitable for clinical or therapeutic use.

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Anti-Human Coagulation Factor III/Tissue Factor Reference Antibody (Mevegtatug, RUO).pdf

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Anti-Human Coagulation Factor III/Tissue Factor Reference Antibody (Mevegtatug, RUO) (HB058086)

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