Anti-Human IL-3R alpha/CD123 Recombinant Nanobody, C-Sortase tag (SAA1297) (HB714033)

Name: Anti-Human IL-3R alpha/CD123 Recombinant Nanobody, C-Sortase tag (SAA1297)
Brand: abinScience
SKU: HB714033
Price: 191 USD
Availability: InStock

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Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HB714033

Описание

Anti-Human IL-3R alpha/CD123 Recombinant Nanobody, C-Sortase tag (SAA1297) (HB714033) is a alpaca monoclonal antibody detecting IL-3R alpha/CD123 in ELISA, FCM, SPR. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, FCM, SPR

Хозяинский вид

Alpaca

Клоональность

Monoclonal

Изотип

VHH-Sortase Tag-6His

ID клона

SAA1297

Цель

CD123, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, IL3R, IL3RA, Interleukin-3 receptor subunit alpha

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Purified by Nickel column

Номер доступа

P26951

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Interleukin-3 receptor subunit alpha (CD123/IL-3Rα) is a ~43 kDa protein. Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program.

1. Huang, S. et al. (1999) Stem cells (Dayton, Ohio) 17, 265-72. PMID: 10527461

Примечание

For research use only

Изображения