

| Каталожный номер | HX089014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-CAV1 Polyclonal Antibody (HX089014) is a rabbit polyclonal antibody detecting CAV1 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Cat, and Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human CAV1 (Ser2-Ser104). | ||||||||
| Цель | CAV, CAV1, Caveolin-1 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Чистота | >95% as determined by SDS-PAGE. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q03135 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Caveolin-1 (CAV1) is a ~20 kDa protein. May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. 1. Vargas, L. et al. (2002) The Journal of biological chemistry 277, 9351-7. PMID: 11751885 2. McMahon, KA. et al. (2009) The EMBO journal 28, 1001-15. PMID: 19262564 3. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217 4. Hwangbo, C. et al. (2016) Oncogene 35, 389-401. PMID: 25893292 | ||||||||
| Примечание | For research use only. |




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