Anti-Human CAV1/Caveolin-1 Recombinant Antibody (SAA1788) (HX089013)

Name: Anti-Human CAV1/Caveolin-1 Recombinant Antibody (SAA1788)
Brand: abinScience
SKU: HX089013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HX089013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1788

Clonality

Monoclonal

Target

CAV, CAV1, Caveolin-1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q03135

RRID

Anti-Human CAV1/Caveolin-1 Antibody (SAA1788) (abinScience Cat# HX089013, RRID:AB_3727550)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Caveolin-1 (CAV1) is a ~20 kDa protein. May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation.

1. Vargas, L. et al. (2002) The Journal of biological chemistry 277, 9351-7. PMID: 11751885

2. McMahon, KA. et al. (2009) The EMBO journal 28, 1001-15. PMID: 19262564

3. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217

4. Hwangbo, C. et al. (2016) Oncogene 35, 389-401. PMID: 25893292

Note

For research use only.

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