Anti-Human CAV1 Monoclonal Antibody (1A515) (HX089025)

Name: Anti-Human CAV1 Monoclonal Antibody (1A515)
Brand: abinScience
SKU: HX089025
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HX089025
Description	Anti-Human CAV1 Monoclonal Antibody (1A515) [1A515] (HX089025) is a mouse monoclonal antibody detecting CAV1 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A515
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human CAV1 (Met1-Ser104).
Target	Caveolin-1, CAV1
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q03135
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Caveolin-1 (CAV1) is a ~20 kDa protein. May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. 1. Vargas, L. et al. (2002) The Journal of biological chemistry 277, 9351-7. PMID: 11751885 2. McMahon, KA. et al. (2009) The EMBO journal 28, 1001-15. PMID: 19262564 3. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217 4. Hwangbo, C. et al. (2016) Oncogene 35, 389-401. PMID: 25893292
Note	For research use only.