Anti-Human Integrin beta 4/CD104 Polyclonal Antibody (HB684024)

Name: Anti-Human Integrin beta 4/CD104 Polyclonal Antibody
Brand: abinScience
SKU: HB684024
Price: 96 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HB684024

Description

Anti-CD104/ITGB4 Polyclonal Antibody (HB684024) is a rabbit polyclonal antibody detecting CD104 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CD104/ITGB4 (Thr1489-Thr1822).

Cible

GP150, Integrin beta-4, CD104, ITGB4

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Purified by antigen affinity column.

Numéro d'accès

P16144

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Integrin beta-4 (CD104/ITGB4) is a ~202 kDa protein. Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling.

1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778

2. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760

3. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464

Note

For research use only.

Images

Western blot

Lane 1: A549 cell lysate
Lane 2: HT-29 cell lysate

Reférences

Fiche technique

Anti-Human Integrin beta 4/CD104 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human Integrin beta 4/CD104 Polyclonal Antibody (HB684024)

Aperçu

Images

Reférences

Fiche technique

SDS