Anti-Human CD104/ITGB4 Recombinant Antibody (65A12), PerCP (HB684147)

Name: Anti-Human CD104/ITGB4 Recombinant Antibody (65A12), PerCP
Brand: abinScience
SKU: HB684147
Price: 268 USD
Availability: InStock

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Overview

Catalog No.	HB684147
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	65A12
Conjugation	PerCP
Clonality	Monoclonal
Target	GP150, Integrin beta-4, CD104, ITGB4
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PerCP
Accession	P16144
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Integrin beta-4 (CD104/ITGB4) is a ~202 kDa protein. Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. 1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778 2. Fujita, M. et al. (2012) The Journal of biological chemistry 287, 12491-500. PMID: 22351760 3. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD104/ITGB4 Recombinant Antibody (65A12), PerCP.pdf

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Anti-Human CD104/ITGB4 Recombinant Antibody (65A12), PerCP (HB684147)

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