Anti-Human Endoglin/CD105 Polyclonal Antibody (HB604014)

Name: Anti-Human Endoglin/CD105 Polyclonal Antibody
Brand: abinScience
SKU: HB604014
Price: 168 USD
Availability: InStock

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Vista general

Número de catálogo

HB604014

Descripción

Anti-CD105/ENG Polyclonal Antibody (HB604014) is a rabbit polyclonal antibody detecting CD105 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human CD105/ENG (Thr27-Gly581).

Objetivo

CD105, END, Endoglin, ENG

Purificación

Purified by antigen affinity column.

Número de acceso

P17813

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454

2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529

3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484

4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773

5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830

6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366

7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410

Nota

For research use only.

Imágenes

Referencias

Datasheet