Anti-Human CD105/ENG Recombinant Antibody (SAA0041), FITC (HB604117)

Name: Anti-Human CD105/ENG Recombinant Antibody (SAA0041), FITC
Brand: abinScience
SKU: HB604117
Price: 223 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50T
100T

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HB604117
Species reactivity	Human
Applications	FCM
Host species	Human
Isotype	IgG1, kappa
Clone ID	SAA0041
Conjugation	FITC
Clonality	Monoclonal
Target	CD105, END, Endoglin, ENG
Endotoxin level	Please contact with the lab for this information.
Associated products	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC
Accession	P17813
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. 1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454 2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529 3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484 4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773 5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830 6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366 7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

Flow CytoMetry

Flow-cytometry using FITC anti-human CD105 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD105 monoclonal antibody (Catalog: HB604117, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet